As a blogger/vlogger/podcaster, what are the best ways to ensure my content doesn't negatively affect my full-time job?

The categories you listed all share one critical feature: to be of value, they basically have to be public, and what's public always carries risk. I don't think there's much of anything you could say that would be completely inoffensive to everyone, but there are certainly minefields that you can and probably should attempt to avoid. Be respectful, don't post anything that would explicitly be bad PR for your business, and make a reasonable attempt to separate off anything having to do with your job from those other activities (e.g. don't mention it's your job, don't try to sell its services, etc.). If those seem obvious, it's because for the most part they are -- it's basically the canned advice that anyone should be able to understand.

That's a tough one, depends on the subject matter and the eyeballs looking. I've created content under an alias for years, especially when discussing topics centered around the military.

Best thing to do is keep your work life and private life as separate as possible. When I'm working on something outside of work, I won't even tell my coworkers. If they find it organically, it's fine but telling workmates about it can be the equivalent to begging for trouble. I also tend to post under an alias as well as avoid using stories that could potentially give away my identity to people I work with. In situations that an alias isn't an option, avoiding work related stories period is a major step in not giving an HR office grounds to use your content against you.