Can you go active from the Reserves with an RE-3 code (General under Honorable) for APFT failure and having been chaptered out of the NG?

The question is what do you offer to the Army. If you already have a RE3 then you are not really a priority. Usually the Army will only take those that need waivers in times of need. If the Army is meeting their goals then they won't bother. If you had issues already then the Army won't want to deal with it. I am not trying to be negative but that is the reality of situation.

Good Grief, NO one is interested in you just passing, hell many units would stomp you for 70 in each event.

I initially enlisted in the USAR as a 13B and often had to deal with my weight and at times passing the PT test. 35 years later as a regular Army LTC I recommend you set your goals higher and train to score at least 80 in each event. that means running 4-7 miles at least 3x per week. Maxing out pushups and situps 3x per day and counducting other physical activites to increase your strength and stamina. you must change your life habits to support your goals. its not easy but it is a matter of choice.