A large blast has hit the Lebanese capital, Beirut, causing widespread damage and injuring many people, officials say.
It is not yet clear what caused the explosion in the port area of the city. Video posted online showed a large mushroom cloud and destroyed buildings.
Hospitals are said to be overwhelmed by casualties.
It comes at a sensitive time with the country's economic collapse reigniting old tensions.
Tensions are also high ahead of the verdict in a trial over the killing of ex-PM Rafik Hariri in 2005. A UN tribunal is due to issue its verdict in the trial of four suspects in the murder by car bomb of Hariri on Friday.