A major drugmaker plans to sell overdose-reversal nasal spray Narcan over the counter

PO1 William "Chip" Nagel good day Brother William, always informational and of the most interesting. Thanks for sharing, have a blessed day!

PO1 William "Chip" Nagel
..."Widely available. But also affordable?
Emergent BioSolutions hasn't yet set a price for the non-prescription version of Narcan. Dasgupta says if it's too expensive, many people at risk of overdose just won't buy it.

"If we have this resource scarcity mentality, that this is an expensive product, then people will not take enough kits to do what they need to do," he says.

In much of the country, governments, insurance companies and nonprofit groups now subsidize naloxone distribution. It's not yet clear how that system will be affected once Narcan is on pharmacy shelves.

One hope is that prices will fall as other drug companies that make naloxone products also seek permission to sell their medications without a prescription.

FDA Commissioner Robert Califf signaled this month his agency plans to approve those applications when they're submitted.

"We think it is time to move to over the counter naloxone," he said at a press conference."

People need to be very careful with narcan. It blocks opioid receptors and can produce dysphoria, tachycardia, and hypertension, it is not benign. You have opioid pain receptors and natural occurring opioid pain modulators. The natural occurring pain modulators are also block causing dysphoria and other responses to extreme pain. The other problem is narcan’s 1/2 life is less than many narcotics and people can go back into respiratory arrest if not monitored and given subsequent doses if needed, ie. they can die! https://www.rxlist.com/narcan-side-effects-drug-center.htm