Posted on Aug 26, 2023
Muscular dystrophy may be able to be prevented, Cincinnati Children's researchers say
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A new study led by Cincinnati Children's Hospital Medical Center finds muscular dystrophy may be able to be prevented. Jerry Lewis began raising money in the 1960s for the disease that decreases mobility and disrupts organ functions.
Children's researchers have tied the primary disease-causing component to part of the mitochondria, which processes nutrients into energy cells needed to survive. Scientists say if they prevent it from functioning, the disease vanishes in mice models.
"We have isolated the primary disease-causing component of muscular dystrophy to the mitochondrial permeability pore," says the study's corresponding author Jeffery Molkentin, Ph.D., in a release. "If we prevent this pore from functioning, dystrophic disease in the mouse models we studied almost completely vanishes. We see the protection lasting past one year of life in the mouse, which translates to about 40 years of life for a human."
Children's researchers have tied the primary disease-causing component to part of the mitochondria, which processes nutrients into energy cells needed to survive. Scientists say if they prevent it from functioning, the disease vanishes in mice models.
"We have isolated the primary disease-causing component of muscular dystrophy to the mitochondrial permeability pore," says the study's corresponding author Jeffery Molkentin, Ph.D., in a release. "If we prevent this pore from functioning, dystrophic disease in the mouse models we studied almost completely vanishes. We see the protection lasting past one year of life in the mouse, which translates to about 40 years of life for a human."
Muscular dystrophy may be able to be prevented, Cincinnati Children's researchers say
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Posted 9 mo ago
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PO1 William "Chip" Nagel
"Children's researchers have tied the primary disease-causing component to part of the mitochondria, which processes nutrients into energy cells needed to survive. Scientists say if they prevent it from functioning, the disease vanishes in mice models."
"Children's researchers have tied the primary disease-causing component to part of the mitochondria, which processes nutrients into energy cells needed to survive. Scientists say if they prevent it from functioning, the disease vanishes in mice models."
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SGT Mary G.
Sounds like the "mitochondrial permeability pore" processes nutirents into energy cells.
Seems like it might have some type of connection to "mitochondrial uncoupling". Watched a video about it, yesterday that said consuming food rich in polyphenols and MCTs gets the liver to tell cells to waste the energy they make, instead of turning it into fat which they ordinarily would do, otherwise.
Seems like it might have some type of connection to "mitochondrial uncoupling". Watched a video about it, yesterday that said consuming food rich in polyphenols and MCTs gets the liver to tell cells to waste the energy they make, instead of turning it into fat which they ordinarily would do, otherwise.
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