My goal is to safely lose 45 LBS and keep it off. What can I do since running is out of the question and I can't drive to the gym?

Spc. Guentger has great advice, add research on caloric intake so you know what you are putting in your body. Find an online program or group that counts calories and exercise. Buy some sort of monitor, like a Fitbit and track your steps, most cell phones even have step and often fit trackers built in. Start walking and exercising. You can purchase bans and go on you tube to find programs, many for free. Ensure that you have spoken with your physician and Knick off the pounds. Thank you for your service.

Victoza

You got this!

The Daniel Fast is a great kick-start to any program and it’s pretty flexible! Also, very clean and easy to follow. It’s in line with several of the other recommendations listed here.

I can't speak much on nutrition but I've written plenty about losing weight. You can always exercise at home.
http://golivelively.com/2015/07/27/myfatlossthoughts/

Diet and anything that safely raises metabolism. Treadmill, stationary bike, walking etc.

If you want to manage your weight, focus on your eating plan. If you want to be more “fit” focus on a workout plan.

Portion control

I'm going to tell you what worked for me.

1- no more fast food (save on the bi-weekly cheat day)

2-come to terms for how often you are permitted to cheat, I find one minor cheat day a week and one major one a month works well for me.

3- Healthy snacks, not all calories are made the same and I've found that as the nutrition value of my food went up that the cravings to eat went down.

4-It is a little on the ikky side, but I would suggest the occasional high fiber day just to clean your crap out...sorry for the pun.

5- Drink extra water.

6-cook all of my own food, I've found that my lazy is more powerful than my munchies. It seems if there is no instant food around and all of my food requires time and effort that I somehow end up sticking to my diet.

7- And on the cheat days when you have them, make it a point to do so in a somewhat ritualistic sort of way, don't just go for a cheap candy bar or potato chips or whatever, find something quality it is the one day of the week to cheat so make the most out of it.