Posted on Nov 2, 2023
Immune boost may protect against multiple hospital-acquired infections
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Posted 6 mo ago
Responses: 1
Lt Col John (Jack) Christensen
...:Further work showed that the vaccine induced certain changes in gene activity in these immune cells. Overall, this created a less inflammatory response to infection. Less inflammation can reduce the risk of sepsis—a deadly response of the body to some hospital-acquired infections. Finally, in preparation for human testing, the team showed that human macrophages had the same gene activity changes when exposed to the vaccine.
“This is very different from developing new antibiotics,” Yan says. “This is using our own immune system to fight against different superbugs.”
Aluminum hydroxide and MLP are already used in FDA-approved vaccines. The researchers are currently planning how to test the vaccine in human volunteers."
...:Further work showed that the vaccine induced certain changes in gene activity in these immune cells. Overall, this created a less inflammatory response to infection. Less inflammation can reduce the risk of sepsis—a deadly response of the body to some hospital-acquired infections. Finally, in preparation for human testing, the team showed that human macrophages had the same gene activity changes when exposed to the vaccine.
“This is very different from developing new antibiotics,” Yan says. “This is using our own immune system to fight against different superbugs.”
Aluminum hydroxide and MLP are already used in FDA-approved vaccines. The researchers are currently planning how to test the vaccine in human volunteers."
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