Simple blood test could help reveal whether melanoma will come back

A simple blood test could reveal who is at high risk of skin cancer recurrence after tumor-removal surgery.

The test can detect fragments of tumor DNA with a simple blood draw to reveal the lingering presence of Stage III melanoma — a metastatic form of the deadliest form of skin cancer — that can't be seen with CT scans. Although the test isn't perfect, it could help flag patients who need aggressive treatment because their cancer is likely to come back.

"We're envisioning the test being used to monitor patients over time (perhaps every month or couple of months in the first 1-3 years after surgery) for an early indication that the melanoma is recurring," study senior author Dr. David Polsky, a dermatologic oncologist at the New York University Grossman School of Medicine, told Live Science in an email.