Best carry self-defense caliber for you?

Sling shot and a Bible,
they both hurt.

Actually I have 3 that I carry depending on what I am wearing.
.380 with shorts
9mm with pants but no coat
.40 with everything else.

I used to carry a Combat Commander in .45 but the polymer framed pistols are much less weight. 

I prefer the knock down power.

all around reliable calaber would have liked a .40 but the 9 is the next best in mho 

Although I have twice as many 9mm than .45. I would rather carry my tarus .45 acp everywhere

.40

After I became an Army Aviator, my personal weapon changed from an M-16A1 to a .38 Special. Near the end of my career it was changed to the 9mm Beretta, which I fell in love with. The .38 Special came in 3 versions...the Colt (least appreciated), the Smith & Wesson (great middle-of-the-road model), and the Ruger (the best of the three). So when I decided to purchase my own 9mm I decided to go with the Ruger P-89 and I have been very happy with it. There are probably other models which would be more preferable with a lot of folks, Glock or Sig probably being more popular, but the Ruger works just fine for me.

A BFG-9000 of course. But lacking one, I'm old school so it's a 45 ACP Springfield xDS. It's always a matter of what you're most comfortable with and trust the most.

.45 For up close and personal knock down power, due to the fact your target will not be getting up right away.

A CZ 75 P07 Duty in 9mm. Gives you 15 rounds. Great trigger pull.