New COVID-19 Antiviral Pills: How Do They Work?

Late last year, two new drugs joined the lineup of options for high-risk patients who may need extra help fighting COVID-19: Merck’s pill molnupiravir, and Pfizer’s pill Paxlovid.

The two pills join remdesivir, an infusion-only drug, as antiviral compounds that attack the SARS-CoV2 virus in different ways. But how exactly do they work, how well do they work, and what makes them complicated to use in real life?