The new obesity drugs work, but it's a dilemma when people have to stop taking them

Over the past few decades, Jonathan Meyers endured several cycles of gaining, shedding, then regaining weight after attempting Keto, high protein, low fat, and calorie-restrictive diets. “I’ve had success, up and down, but I always regain the weight,” says Meyers, a digital strategist at an environmental nonprofit.

But on Zepbound – the newest GLP-1 agonistdrug to launch – Meyers lost 35 pounds and loves feeling free from hunger. Without what he calls “food noise” – the gnawing compulsion to eat – he consumes less and moves more.