Traces of the nerve agent allegedly used to poison Russian politician Alexei Navalny were found on a bottle in the hotel room where he stayed before falling ill, his team has said.
Mr Navalny collapsed on a flight in Siberia in August. Germany says he was poisoned with a Novichok nerve agent.
It was previously thought that he might have been targeted at the airport.
"Now we understand: It was done before he left his room to reach the airport," a post on his Instagram account says.
Mr Navalny, Russia's most high profile opposition figure and a leading critic of Russian President Vladimir Putin, is currently receiving treatment in the German capital Berlin.
His team alleges he was poisoned on the orders of Mr Putin.
The Kremlin denies any involvement in the case and says its doctors found no evidence that a nerve agent was used.
No official investigation has been launched in Russia, although the head of Mr Navalny's anti-corruption foundation Ivan Zhdanov tweeted that, as part of preliminary enquiries, an investigator from Tomsk - where the attack happened - wanted to question two of the foundation's employees who were with Mr Navalny when he fell ill.