Thousands are gathered in Washington DC to commemorate the 1963 civil rights March on Washington and in protest of police violence.
The families of black Americans shot or killed by police will speak at the same site where Martin Luther King Jr delivered his I Have a Dream speech.
Friday's event is called the Commitment March: Get Your Knee Off Our Necks, a reference to George Floyd's death.
It follows renewed protests over the police shooting of Jacob Blake.
The relatives of Mr Blake, Mr Floyd, Breonna Taylor and Eric Garner are expected to deliver speeches at the march.