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Sir Alexander Fleming FRS FRSE FRCS[1] (6 August 1881 – 11 March 1955) was a Scottish biologist, physician, microbiologist, and pharmacologist. His best-known discoveries are the enzyme lysozyme in 1923 and the world's first antibiotic substance benzylpenicillin (Penicillin G) from the mould Penicillium notatum in 1928, for which he shared the Nobel Prize in Physiology or Medicine in 1945 with Howard Florey and Ernst Boris Chain.[3][4][5] He wrote many articles on bacteriology, immunology, and chemotherapy.
Fleming was knighted for his scientific achievements in 1944.[6] In 1999, he was named in Time magazine's list of the 100 Most Important People of the 20th century. In 2002, he was chosen in the BBC's television poll for determining the 100 Greatest Britons, and in 2009, he was also voted third "greatest Scot" in an opinion poll conducted by STV, behind only Robert Burns and William Wallace.
Fleming was knighted for his scientific achievements in 1944.[6] In 1999, he was named in Time magazine's list of the 100 Most Important People of the 20th century. In 2002, he was chosen in the BBC's television poll for determining the 100 Greatest Britons, and in 2009, he was also voted third "greatest Scot" in an opinion poll conducted by STV, behind only Robert Burns and William Wallace.
Alexander Fleming - Wikipedia
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Alexander Fleming's Discovery of Penicillin
Chronology of the discovery of Penicilin
Thank you my friend Maj Marty Hogan for making us aware that August 6 is the anniversary of the birth of Scottish physician, microbiologist, and pharmacologist Sir Alexander Fleming FRS FRSE FRCS who is best-known discoveries are the enzyme lysozyme in 1923 and the world's first antibiotic substance benzylpenicillin (Penicillin G) from the mould Penicillium notatum in 1928, for which he shared the Nobel Prize in Physiology or Medicine in 1945 with Howard Florey and Ernst Boris Chain.
Rest in peace Sir Alexander Fleming!
Background from nobelprize.org/nobel_prizes/medicine/laureates/1945/fleming-bio.html
"Sir Alexander Fleming - Biographical
Sir Alexander Fleming was born at Lochfield near Darvel in Ayrshire, Scotland on August 6th, 1881. He attended Louden Moor School, Darvel School, and Kilmarnock Academy before moving to London where he attended the Polytechnic. He spent four years in a shipping office before entering St. Mary's Medical School, London University. He qualified with distinction in 1906 and began research at St. Mary's under Sir Almroth Wright, a pioneer in vaccine therapy. He gained M.B., B.S., (London), with Gold Medal in 1908, and became a lecturer at St. Mary's until 1914. He served throughout World War I as a captain in the Army Medical Corps, being mentioned in dispatches, and in 1918 he returned to St.Mary's. He was elected Professor of the School in 1928 and Emeritus Professor of Bacteriology, University of London in 1948. He was elected Fellow of the Royal Society in 1943 and knighted in 1944.
Early in his medical life, Fleming became interested in the natural bacterial action of the blood and in antiseptics. He was able to continue his studies throughout his military career and on demobilization he settled to work on antibacterial substances which would not be toxic to animal tissues. In 1921, he discovered in «tissues and secretions» an important bacteriolytic substance which he named Lysozyme. About this time, he devised sensitivity titration methods and assays in human blood and other body fluids, which he subsequently used for the titration of penicillin. In 1928, while working on influenza virus, he observed that mould had developed accidently on a staphylococcus culture plate and that the mould had created a bacteria-free circle around itself. He was inspired to further experiment and he found that a mould culture prevented growth of staphylococci, even when diluted 800 times. He named the active substance penicillin.
Sir Alexander wrote numerous papers on bacteriology, immunology and chemotherapy, including original descriptions of lysozyme and penicillin. They have been published in medical and scientific journals.
Fleming, a Fellow of the Royal College of Surgeons (England), 1909, and a Fellow of the Royal College of Physicians (London), 1944, has gained many awards. They include Hunterian Professor (1919), Arris and Gale Lecturer (1929) and Honorary Gold Medal (1946) of the Royal College of Surgeons; Williams Julius Mickle Fellowship, University of London (1942); Charles Mickle Fellowship, University of Toronto (1944); John Scott Medal, City Guild of Philadelphia (1944); Cameron Prize, University of Edinburgh (1945); Moxon Medal, Royal College of Physicians (1945); Cutter Lecturer, Harvard University (1945); Albert Gold Medal, Royal Society of Arts (1946); Gold Medal, Royal Society of Medicine (1947); Medal for Merit, U.S.A. (1947); and the Grand Cross of Alphonse X the Wise, Spain (1948).
He served as President of the Society for General Microbiology, he was a Member of the Pontifical Academy of Science and Honorary Member of almost all the medical and scientific societies of the world. He was Rector of Edinburgh University during 1951-1954, Freeman of many boroughs and cities and Honorary Chief Doy-gei-tau of the Kiowa tribe. He was also awarded doctorate, honoris causa, degrees of almost thirty European and American Universities.
In 1915, Fleming married Sarah Marion McElroy of Killala, Ireland, who died in 1949. Their son is a general medical practitioner.
Fleming married again in 1953, his bride was Dr. Amalia Koutsouri-Voureka, a Greek colleague at St. Mary's.
In his younger days he was a keen member of the Territorial Army and he served from 1900 to 1914 as a private in the London Scottish Regiment.
Dr Fleming died on March 11th in 1955 and is buried in St. Paul's Cathedral.
From Nobel Lectures, Physiology or Medicine 1942-1962, Elsevier Publishing Company, Amsterdam, 1964"
Alexander Fleming's Discovery of Penicillin
Chronology of the discovery of Penicilin
https://www.youtube.com/watch?v=5RGs-2eNnjM
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Rest in peace Sir Alexander Fleming!
Background from nobelprize.org/nobel_prizes/medicine/laureates/1945/fleming-bio.html
"Sir Alexander Fleming - Biographical
Sir Alexander Fleming was born at Lochfield near Darvel in Ayrshire, Scotland on August 6th, 1881. He attended Louden Moor School, Darvel School, and Kilmarnock Academy before moving to London where he attended the Polytechnic. He spent four years in a shipping office before entering St. Mary's Medical School, London University. He qualified with distinction in 1906 and began research at St. Mary's under Sir Almroth Wright, a pioneer in vaccine therapy. He gained M.B., B.S., (London), with Gold Medal in 1908, and became a lecturer at St. Mary's until 1914. He served throughout World War I as a captain in the Army Medical Corps, being mentioned in dispatches, and in 1918 he returned to St.Mary's. He was elected Professor of the School in 1928 and Emeritus Professor of Bacteriology, University of London in 1948. He was elected Fellow of the Royal Society in 1943 and knighted in 1944.
Early in his medical life, Fleming became interested in the natural bacterial action of the blood and in antiseptics. He was able to continue his studies throughout his military career and on demobilization he settled to work on antibacterial substances which would not be toxic to animal tissues. In 1921, he discovered in «tissues and secretions» an important bacteriolytic substance which he named Lysozyme. About this time, he devised sensitivity titration methods and assays in human blood and other body fluids, which he subsequently used for the titration of penicillin. In 1928, while working on influenza virus, he observed that mould had developed accidently on a staphylococcus culture plate and that the mould had created a bacteria-free circle around itself. He was inspired to further experiment and he found that a mould culture prevented growth of staphylococci, even when diluted 800 times. He named the active substance penicillin.
Sir Alexander wrote numerous papers on bacteriology, immunology and chemotherapy, including original descriptions of lysozyme and penicillin. They have been published in medical and scientific journals.
Fleming, a Fellow of the Royal College of Surgeons (England), 1909, and a Fellow of the Royal College of Physicians (London), 1944, has gained many awards. They include Hunterian Professor (1919), Arris and Gale Lecturer (1929) and Honorary Gold Medal (1946) of the Royal College of Surgeons; Williams Julius Mickle Fellowship, University of London (1942); Charles Mickle Fellowship, University of Toronto (1944); John Scott Medal, City Guild of Philadelphia (1944); Cameron Prize, University of Edinburgh (1945); Moxon Medal, Royal College of Physicians (1945); Cutter Lecturer, Harvard University (1945); Albert Gold Medal, Royal Society of Arts (1946); Gold Medal, Royal Society of Medicine (1947); Medal for Merit, U.S.A. (1947); and the Grand Cross of Alphonse X the Wise, Spain (1948).
He served as President of the Society for General Microbiology, he was a Member of the Pontifical Academy of Science and Honorary Member of almost all the medical and scientific societies of the world. He was Rector of Edinburgh University during 1951-1954, Freeman of many boroughs and cities and Honorary Chief Doy-gei-tau of the Kiowa tribe. He was also awarded doctorate, honoris causa, degrees of almost thirty European and American Universities.
In 1915, Fleming married Sarah Marion McElroy of Killala, Ireland, who died in 1949. Their son is a general medical practitioner.
Fleming married again in 1953, his bride was Dr. Amalia Koutsouri-Voureka, a Greek colleague at St. Mary's.
In his younger days he was a keen member of the Territorial Army and he served from 1900 to 1914 as a private in the London Scottish Regiment.
Dr Fleming died on March 11th in 1955 and is buried in St. Paul's Cathedral.
From Nobel Lectures, Physiology or Medicine 1942-1962, Elsevier Publishing Company, Amsterdam, 1964"
Alexander Fleming's Discovery of Penicillin
Chronology of the discovery of Penicilin
https://www.youtube.com/watch?v=5RGs-2eNnjM
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